SCHEMBL950540

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28002049	0.84	ALDH1A1 (0.62)	ALDH1A1LMNACYP19A1
	SCHEMBL14665418	0.83	ALDH1A1 (0.61)	ALDH1A1LMNACYP19A1
	SCHEMBL950753	0.83	ALDH1A1 (0.61)	ALDH1A1LMNACYP19A1
	SCHEMBL20192085	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL33518	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL23865155	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL7173571	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL16188009	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL20505978	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1
	SCHEMBL7538065	0.83	MAPT (0.53)	ALDH1A1LMNACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.