Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SYK | P43405 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18274598 | 0.88 | CYP3A4 (0.56) | CYP3A4TSHRSYKMAPTTP53 | |
| SCHEMBL6327495 | 0.84 | CYP3A4 (0.81) | CYP3A4TSHRSYKMAPTTP53 | |
| SCHEMBL34468055 | 0.82 | CYP3A4 (0.66) | CYP3A4TSHRSYKMAPTTP53 | |
| SCHEMBL16947038 | 0.81 | ALDH1A1 (0.56) | CYP3A4TSHRMAPTKMT2AMEN1 | |
| SCHEMBL29678179 | 0.81 | CYP3A4 (1.00) | CYP3A4TSHRSYKMAPTTP53 | |
| SCHEMBL219995 | 0.81 | CYP3A4 (1.00) | CYP3A4TSHRSYKMAPTTP53 | |
| SCHEMBL18201524 | 0.80 | ALDH1A1 (0.50) | CYP3A4TSHRSYKMAPTKMT2A | |
| SCHEMBL29406240 | 0.80 | ALDH1A1 (0.54) | CYP3A4TSHRMAPTKMT2AMEN1 | |
| SCHEMBL26604601 | 0.80 | ALDH1A1 (0.54) | CYP3A4TSHRMAPTKMT2AMEN1 | |
| SCHEMBL1727357 | 0.79 | CYP3A4 (0.57) | CYP3A4TSHRSYKMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295126-B1 | ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0295127-B1 | ARYLAMINE POLYMERS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0295125-B1 | POLYARYLAMINE COMPOUNDS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4935487-A | Carbonate-arylamine polymer | XEROX CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4806444-A | Arylamine polymers and systems utilizing arylamine polymers | XEROX CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| US-4806443-A | Polyarylamine compounds and systems utilizing polyarylamine compounds | XEROX CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0295125-A2 | Polyarylamine compounds | XEROX CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0295126-A2 | Arylamine-containing polyhydroxy ether resins | XEROX CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0295127-A2 | Arylamine polymers | XEROX CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |