Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 3/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921475 | 0.94 | CYP3A4 (0.76) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL29678179 | 0.90 | CYP3A4 (1.00) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL219995 | 0.90 | CYP3A4 (1.00) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL1920769 | 0.88 | CYP3A4 (0.86) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL21311932 | 0.85 | HSD17B1 (0.67) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL9505497 | 0.84 | CYP3A4 (0.67) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL24057847 | 0.84 | ALDH1A1 (0.65) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL18873125 | 0.84 | ALDH1A1 (0.65) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL8352093 | 0.84 | CYP3A4 (0.79) | CYP3A4TSHRKMT2AMAPTMEN1 | |
| SCHEMBL2794153 | 0.84 | ALDH1A1 (0.65) | CYP3A4TSHRKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734610-B | Meta-substituted phenol compound and preparation method and application thereof | 广东工业大学 | 2022-02-15 | — | — | CN | disclosed |
| US-6919357-B2 | α adrenergic agents | MOLECULAR DESIGN INTERNATIONAL INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20030092741-A1 | Novel alpha adrenergic agents | MOLECTULAR DESIGN INTERNATIONAL INC. | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092741-A1 | Novel alpha adrenergic agents | ADRA1D, ADRB1, ADRA1B | CYP3A4 1191/4885TSHR 3454/4885KMT2A 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.