Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 4/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764072 | 0.96 | RARB (0.50) | HSD11B1RARBPSMB5RARARARG | |
| SCHEMBL9764331 | 0.95 | RARB (0.52) | HSD11B1RARBRARARARGCTSV | |
| SCHEMBL9764026 | 0.95 | RARB (0.52) | HSD11B1RARBRARARARGCTSV | |
| SCHEMBL9763731 | 0.95 | RARB (0.52) | HSD11B1RARBRARARARGCTSV | |
| SCHEMBL9763632 | 0.95 | RARB (0.52) | HSD11B1RARBRARARARGCTSV | |
| SCHEMBL9763649 | 0.95 | RARB (0.52) | HSD11B1RARBRARARARGCTSV | |
| SCHEMBL9763543 | 0.92 | RARB (0.39) | HSD11B1RARBPSMB5RARARARG | |
| SCHEMBL9764364 | 0.87 | TP53 (0.41) | — | |
| SCHEMBL9221770 | 0.84 | HSD11B1 (0.48) | HSD11B1RARBPSMB5RARARARG | |
| SCHEMBL8095372 | 0.83 | RARB (0.48) | HSD11B1RARBPSMB5RARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387032-B1 | TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | CHISSO CORP (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |