Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505504 | 0.92 | HSD11B1 (0.47) | RARBHSD11B1RARARARGPSMB5 | |
| SCHEMBL9764072 | 0.90 | RARB (0.50) | RARBHSD11B1RARARARGPSMB5 | |
| SCHEMBL9764364 | 0.89 | TP53 (0.41) | NPC1RAB9ATP53SMN1; SMN2BACE1 | |
| SCHEMBL9763731 | 0.89 | RARB (0.52) | RARBHSD11B1RARARARGHSD17B10 | |
| SCHEMBL9763632 | 0.89 | RARB (0.52) | RARBHSD11B1RARARARGHSD17B10 | |
| SCHEMBL9763649 | 0.89 | RARB (0.52) | RARBHSD11B1RARARARGHSD17B10 | |
| SCHEMBL9764331 | 0.89 | RARB (0.52) | RARBHSD11B1RARARARGHSD17B10 | |
| SCHEMBL9764026 | 0.89 | RARB (0.52) | RARBHSD11B1RARARARGHSD17B10 | |
| SCHEMBL8110566 | 0.86 | PDK2 (0.37) | RARBBACE1PSMB5 | |
| SCHEMBL9226851 | 0.84 | PTGS2 (0.44) | RARBHSD11B1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |