Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506639 | 0.80 | CA1 (0.40) | POLBLNPEPCA1CA2CA7 | |
| SCHEMBL9504651 | 0.78 | METAP2 (0.43) | POLBCA1CA2CA7CA9 | |
| SCHEMBL9506681 | 0.78 | METAP2 (0.43) | POLBCA1CA2CA7CA9 | |
| SCHEMBL18580070 | 0.78 | TACR1 (0.49) | POLBSLC1A1LNPEPCA1CA2 | |
| Hydrochloric Acid SCHEMBL8817784 | 0.75 | TACR1 (0.49) | POLBSLC1A1CA1CA2CA7 | |
| SCHEMBL9694637 | 0.74 | TACR1 (0.39) | POLBLNPEPTACR1METAP2 | |
| SCHEMBL9504654 | 0.74 | CA1 (0.46) | POLBCA1CA2CA7CA9 | |
| SCHEMBL9504650 | 0.74 | CA1 (0.46) | POLBCA1CA2CA7CA9 | |
| SCHEMBL10475483 | 0.72 | CA1 (0.50) | POLBCA1CA2CA7CA9 | |
| SCHEMBL1355001 | 0.72 | SLC6A2 (0.44) | POLBKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |