Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.43 |
| ▸ | METAP1 | P53582 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506681 | 1.00 | METAP2 (0.43) | METAP2METAP1CTSSTACR1POLB | |
| SCHEMBL9694637 | 0.88 | TACR1 (0.39) | METAP2METAP1CTSSTACR1POLB | |
| SCHEMBL9506639 | 0.80 | CA1 (0.40) | CTSSPOLBCTSLCTSBCA1 | |
| SCHEMBL9518173 | 0.78 | METAP2 (0.47) | METAP2METAP1CTSSCTSLCTSB | |
| SCHEMBL9518165 | 0.78 | METAP2 (0.47) | METAP2METAP1CTSSCTSLCTSB | |
| SCHEMBL9505567 | 0.78 | POLB (0.38) | METAP2TACR1POLBCA1CA2 | |
| SCHEMBL9506657 | 0.76 | POLB (0.38) | CTSSTACR1POLBCTSLCTSB | |
| SCHEMBL8116441 | 0.75 | CA1 (0.55) | CTSSPOLBCTSLCTSBCA1 | |
| SCHEMBL8116438 | 0.75 | CA1 (0.55) | CTSSPOLBCTSLCTSBCA1 | |
| SCHEMBL9770915 | 0.73 | METAP2 (0.53) | METAP2METAP1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003472-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |