Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503027 | 0.93 | MEN1 (0.58) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL9503848 | 0.89 | ACAT1 (0.60) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL9505568 | 0.89 | ACAT1 (0.60) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL9502181 | 0.88 | SMPD1 (0.55) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL9503292 | 0.88 | PLK1 (0.65) | PLA2G4BTP53MAPTGAAMAPK1 | |
| SCHEMBL9506207 | 0.85 | ACAT1 (0.55) | TP53MEN1MAPTKMT2AHTT | |
| SCHEMBL9502439 | 0.80 | MAPT (0.62) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL9505675 | 0.79 | MAPT (0.61) | PLA2G4BTP53MEN1MAPTKMT2A | |
| SCHEMBL10597666 | 0.78 | FAAH (0.73) | GAA | |
| SCHEMBL9502027 | 0.78 | ACAT1 (0.62) | TP53MEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543891-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |