Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556791 | 0.84 | SPHK1 (0.34) | SPHK1EPHX1HPGD | |
| SCHEMBL10528950 | 0.84 | SPHK1 (0.35) | SPHK1EPHX1HPGD | |
| SCHEMBL9186816 | 0.82 | SPHK1 (0.32) | SPHK1EPHX1HPGD | |
| SCHEMBL9444993 | 0.81 | EPHX1 (0.33) | NR1H2SPHK1EPHX1HPGD | |
| SCHEMBL9444999 | 0.81 | EPHX1 (0.33) | NR1H2SPHK1EPHX1HPGD | |
| SCHEMBL7365732 | 0.81 | RABGGTB (0.33) | SPHK1EPHX1 | |
| SCHEMBL7365730 | 0.81 | RABGGTB (0.33) | SPHK1EPHX1 | |
| SCHEMBL9556455 | 0.81 | SPHK1 (0.34) | SPHK1EPHX1 | |
| SCHEMBL7394682 | 0.81 | EPHX1 (0.32) | SPHK1EPHX1HPGD | |
| SCHEMBL7394683 | 0.81 | EPHX1 (0.32) | SPHK1EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003472-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |