Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333709 | 1.00 | KMT2A (0.59) | KMT2AMEN1LTA4HALDH1A1LMNA | |
| SCHEMBL9505607 | 0.80 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29508217 | 0.75 | ALDH1A1 (0.88) | KMT2ALTA4HALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17444439 | 0.75 | OPRM1 (0.53) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7331713 | 0.73 | ALDH1A1 (0.56) | KMT2AMEN1LTA4HALDH1A1LMNA | |
| SCHEMBL873542 | 0.73 | ALDH1A1 (0.74) | KMT2ALTA4HALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13590529 | 0.73 | ACKR3 (0.66) | LTA4HCHRM2CHRM1HTR2AHTR2B | |
| SCHEMBL1395845 | 0.72 | LTA4H (0.61) | LTA4HALDH1A1SMN1; SMN2GAAKDM4E | |
| Pramoxine SCHEMBL2505808 | 0.72 | ALDH1A1 (0.75) | KMT2AMEN1LTA4HALDH1A1LMNA | |
| SCHEMBL3569060 | 0.71 | LTA4H (0.67) | LTA4HALDH1A1SMN1; SMN2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |