SCHEMBL9505730

SCHEMBL9505730

COCc1ccc(COC)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
MAOA P21397 1/20 0.37
DYRK1A Q13627 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA2 P00918 1/20 0.36
ALDH1A1 P00352 2/20 0.35
PRKCE Q02156 2/20 0.35
MYLK Q15746 2/20 0.35
MEN1 O00255 1/20 0.35
PRKCG P05129 1/20 0.35
MAPT P10636 1/20 0.35
PRKCA P17252 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35
PDK2 Q15119 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19982659 0.88 LMNA (0.37) LMNATP53TDP1POLBL3MBTL1
SCHEMBL8750514 0.88 LMNA (0.39) LMNATP53MAOADYRK1ATDP1
SCHEMBL12993001 0.86 LOXL2 (0.38) LMNATP53KDM4E
SCHEMBL8750643 0.82 NPC1 (0.42) LMNATP53MAOADYRK1ATDP1
SCHEMBL4965724 0.82 LMNA (0.40) LMNATP53MAOADYRK1ATDP1
SCHEMBL20897164 0.80 PDK2 (0.42) LMNATP53MAOADYRK1ACA2
SCHEMBL1145658 0.80 KDM4E (0.51) LMNATP53TDP1L3MBTL1ALDH1A1
SCHEMBL18713938 0.77 SKP2 (0.53) LMNATP53MAOADYRK1ATDP1
SCHEMBL7704446 0.77 KMT2A (0.46) MAOAPOLBCA2ALDH1A1MEN1
SCHEMBL755548 0.77 PTPN1 (0.39) LMNATP53MAOADYRK1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311387-B1 AROMATIC AMINE RESINS, THEIR PRODUCTION PROCESS AND THERMOSETTING RESIN COMPOSITIONS MAKING USE OF THE SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-11 EP disclosed
EP-0342943-B1 THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5145949-A Production process for making aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
US-5106953-A Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-21 US disclosed
US-5051494-A A bismaleimide and an amino resin MITSUI TOATSU CHEMICALS, INC. (JP) 1991-09-24 US disclosed
US-4959443-A HIGH STRENGTH, REACTION OF ARALKYL ALCOHOL AND AROMATIC AMINE MITSUI TOATSU CHEMICALS, INC. (JP) 1990-09-25 US disclosed
US-4937318-A Aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1990-06-26 US disclosed
EP-0342943-A1 Thermosetting resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-23 EP disclosed