SCHEMBL4965724

SCHEMBL4965724

COCc1ccc(COC)c(COC)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
PRKCE Q02156 2/20 0.38
MYLK Q15746 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PRKCG P05129 1/20 0.38
MAPT P10636 1/20 0.38
PRKCA P17252 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
CA2 P00918 1/20 0.38
PDK2 Q15119 1/20 0.37
MAOA P21397 1/20 0.36
DYRK1A Q13627 1/20 0.36
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FFAR1 O14842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434129 0.84 PDK2 (0.42) LMNATP53PRKCEMYLKTDP1
Hydrochloric Acid SCHEMBL6799727 0.83 MAOB (0.42) PRKCEMYLKALDH1A1
SCHEMBL10015634 0.82 LMNA (0.41) LMNATP53TDP1ALDH1A1CA2
SCHEMBL9505730 0.82 LMNA (0.41) LMNATP53PRKCEMYLKTDP1
SCHEMBL8303294 0.81 KDM4E (0.52) LMNAMEN1APEX1KMT2AKDM4E
SCHEMBL755548 0.80 PTPN1 (0.39) LMNATP53PRKCEMYLKTDP1
SCHEMBL8954831 0.80 IDO1 (0.44) LMNATP53ALDH1A1CA2NPC1
SCHEMBL25446785 0.80 IDO1 (0.47) ALDH1A1MAPTCA2KDM4E
SCHEMBL8750671 0.80 TDP1 (0.42) LMNATP53PRKCEMYLKTDP1
SCHEMBL5936401 0.80 PTPN1 (0.39) LMNATP53PRKCEMYLKTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed
EP-0284385-A2 Aralkylphenolic resin molding material MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B LMNA 4486/4885TP53 4109/4885PRKCE 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.