Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421048 | 0.83 | CTSK (0.60) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL22004938 | 0.81 | CTSK (0.58) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL18775037 | 0.81 | CTSK (0.58) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL10706801 | 0.80 | CAPN1 (0.55) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL10706806 | 0.80 | CAPN1 (0.55) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL10825080 | 0.80 | CAPN1 (0.55) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL29577590 | 0.78 | CTSK (0.55) | CTSKS1PR4S1PR1CTSSCTSB | |
| SCHEMBL9505358 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL9505878 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL7317922 | 0.77 | MMP1 (0.47) | CTSKS1PR4S1PR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320118-B1 | PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-4935404-A | ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1990-06-19 | — | — | US | disclosed |
| EP-0320118-A2 | Peptides with collagenase inhibiting activity | BEECHAM GROUP PLC (GB) | 1989-06-14 | — | — | EP | disclosed |