Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348381 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1PTPN1 | |
| SCHEMBL7314892 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1PTPN1 | |
| SCHEMBL7378604 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1PTPN1 | |
| SCHEMBL7343916 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BHDAC1PTPN1 | |
| SCHEMBL7352151 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BHDAC1HDAC3HDAC6 | |
| SCHEMBL9505510 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BHDAC1HDAC3POLB | |
| SCHEMBL10444991 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BHDAC1PTPN1ALDH1A1 | |
| SCHEMBL7436661 | 0.77 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL8408579 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BPTPN1ALDH1A1 | |
| SCHEMBL9295158 | 0.75 | ITGB3 (0.43) | ITGB3ITGA2BHDAC1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352249-B1 | NOVEL PLATELET-AGGREGATION INHIBITORS | Monsanto Company (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | claimed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | disclosed |