Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | NPY4R | P50391 | 4/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | NPY1R | P25929 | 3/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314892 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1NPY4RNPY5R | |
| SCHEMBL7378604 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1NPY4RNPY5R | |
| SCHEMBL7343916 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BPTPN1NPY4RNPY5R | |
| SCHEMBL9505510 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BHDAC1CTSD | |
| SCHEMBL10444991 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1HDAC1HDAC7 | |
| SCHEMBL9505922 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1HDAC1 | |
| SCHEMBL8408579 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BPTPN1NPY4RNPY5R | |
| SCHEMBL7318679 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7436661 | 0.76 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL7343514 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352249-B1 | NOVEL PLATELET-AGGREGATION INHIBITORS | Monsanto Company (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | claimed |
| US-4879313-A | ANTICOAGULANTS | MOSANTO COMPANY (US) | 1989-11-07 | — | — | US | claimed |
| EP-0352249-B1 | NOVEL PLATELET-AGGREGATION INHIBITORS | Monsanto Company (US) | 1993-09-08 | — | — | EP | disclosed |
| US-4992463-A | Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation | MONSANTO COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | disclosed |
| US-4879313-A | ANTICOAGULANTS | MOSANTO COMPANY (US) | 1989-11-07 | — | — | US | disclosed |