Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343916 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BCTSDHDAC1 | |
| SCHEMBL7348381 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BCTSDHDAC1 | |
| SCHEMBL7378604 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BCTSDHDAC1 | |
| SCHEMBL7314892 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BCTSDHDAC1 | |
| SCHEMBL8408579 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL10444991 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BCTSDHDAC1 | |
| SCHEMBL9505922 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2BPOLBHDAC3HDAC1 | |
| SCHEMBL7318679 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7357729 | 0.78 | L3MBTL1 (0.66) | POLBHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7343514 | 0.75 | ITGB3 (0.48) | ITGB3ITGA2BHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352249-B1 | NOVEL PLATELET-AGGREGATION INHIBITORS | Monsanto Company (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | claimed |
| EP-0352249-A1 | Novel platelet-aggregation inhibitors | Monsanto Company (US) | 1990-01-24 | — | — | EP | disclosed |