SCHEMBL9505954

SCHEMBL9505954

Cc1nc2nc(O)cc(N)n2n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 5/20 0.35
LMNA P02545 4/20 0.35
TP53 P04637 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4C Q9H3R0 1/20 0.35
DPP4 P27487 1/20 0.35
POLB P06746 1/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
AHR P35869 1/20 0.33
MAPK1 P28482 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504134 0.80 TP53 (0.36) KDM4ENPSR1ALDH1A1LMNATP53
SCHEMBL10887539 0.69 ALDH1A1 (0.43) KDM4ENPSR1ALDH1A1LMNASMN1; SMN2
SCHEMBL4613719 0.68 L3MBTL1 (0.46) ALDH1A1LMNATP53SMN1; SMN2KDM4C
SCHEMBL31727996 0.67 ALDH1A1 (0.39) KDM4ENPSR1ALDH1A1LMNATP53
SCHEMBL3419186 0.66 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2POLBMEN1
SCHEMBL11916282 0.66 ALDH1A1 (0.33) KDM4ENPSR1ALDH1A1LMNATP53
SCHEMBL5200214 0.65 NPSR1 (0.41) KDM4ENPSR1ALDH1A1TP53SMN1; SMN2
SCHEMBL21565452 0.65 NPSR1 (0.49) KDM4ENPSR1ALDH1A1SMN1; SMN2POLB
SCHEMBL9822135 0.64 TP53 (0.37) KDM4ENPSR1ALDH1A1LMNATP53
SCHEMBL19194488 0.64 TP53 (0.40) KDM4ENPSR1ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
US-4628082-A Derivatives of azobarbituric acid or salts or complexes thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-4622391-A ORGANIC PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
EP-0074515-B1 AZO DERIVATIVES OF BARBITURIC ACID, THEIR SOLID SOLUTIONS, INSERTION COMPOUNDS AND INTERCALATION COMPOUNDS BAYER AG (DE) 1986-08-20 EP disclosed
EP-0073463-B1 INSERTION COMPOUNDS, INTERCALATION COMPOUNDS AND SOLID SOLUTIONS OF COLOURED METALLIC ORGANIC DERIVATIVES BAYER AG (DE) 1985-10-23 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed
EP-0074515-A1 Azo derivatives of barbituric acid, their solid solutions, insertion compounds and intercalation compounds BAYER AG (DE) 1983-03-23 EP disclosed
EP-0073463-A1 Insertion compounds, intercalation compounds and solid solutions of coloured metallic organic derivatives BAYER AG (DE) 1983-03-09 EP disclosed