SCHEMBL9504134

SCHEMBL9504134

Cc1nc2nc(O)cc(O)n2n1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.36
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4C Q9H3R0 1/20 0.36
POLB P06746 1/20 0.36
AHR P35869 1/20 0.35
MAPK1 P28482 3/20 0.34
HPGD P15428 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 2/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4613719 0.83 L3MBTL1 (0.46) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL9505954 0.80 KDM4E (0.35) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL19194488 0.79 TP53 (0.40) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL9822135 0.79 TP53 (0.37) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL13325670 0.76 ALDH1A1 (0.40) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL9141762 0.73 L3MBTL1 (0.48) TP53LMNAALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL11583625 0.73 NOS2 (0.42) TP53ALDH1A1L3MBTL1SMN1; SMN2POLB
SCHEMBL5200396 0.73 KDM4E (0.46) TP53LMNAALDH1A1SMN1; SMN2MAPK1
SCHEMBL9592250 0.71 CA12 (0.40)
SCHEMBL20511415 0.71 PDE10A (0.42) TP53SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0297397-A2 Preparation of diazo and azo compounds BAYER AG (DE) 1989-01-04 EP disclosed
US-4628082-A Derivatives of azobarbituric acid or salts or complexes thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-4622391-A ORGANIC PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
EP-0074515-B1 AZO DERIVATIVES OF BARBITURIC ACID, THEIR SOLID SOLUTIONS, INSERTION COMPOUNDS AND INTERCALATION COMPOUNDS BAYER AG (DE) 1986-08-20 EP disclosed
EP-0073463-B1 INSERTION COMPOUNDS, INTERCALATION COMPOUNDS AND SOLID SOLUTIONS OF COLOURED METALLIC ORGANIC DERIVATIVES BAYER AG (DE) 1985-10-23 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed