Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084003 | 0.92 | HPGD (0.70) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL7489809 | 0.92 | HPGD (0.70) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL3626811 | 0.87 | RAB9A (0.72) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL28591026 | 0.86 | RAB9A (0.66) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8553437 | 0.86 | RAB9A (0.73) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8050007 | 0.86 | RAB9A (0.73) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL13969475 | 0.85 | RAB9A (0.64) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL31568627 | 0.82 | MGLL (0.59) | HPGDNPSR1MAPTSMN1; SMN2POLB | |
| SCHEMBL950598 | 0.81 | HPGD (0.59) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL25042562 | 0.81 | HPGD (0.58) | HPGDNPSR1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044144-A2 | CHIRAL TETRA-HYDRO BETA-CARBOLIC DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | UNIVERSITE DE LILLE 2, UNIVERSITÉ DU DROIT ET DE LA SANTÉ (FR) | 2008-04-17 | — | — | WO | disclosed |