Styrene

Styrene

SCHEMBL9505984

BrC(Br)=Cc1ccccc1.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TSHR P16473 2/20 0.58
FBP1 P09467 3/20 0.41
AKR1C3 P42330 1/20 0.41
MAPT P10636 6/20 0.39
HTT P42858 2/20 0.39
RAB9A P51151 2/20 0.39
MITF O75030 1/20 0.39
LMNA P02545 1/20 0.39
RECQL P46063 1/20 0.39
PAX8 Q06710 1/20 0.39
AKR1C1 Q04828 1/20 0.35
ESR1 P03372 1/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.34
GAA P10253 1/20 0.34
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9717243 0.96 ALDH1A1 (0.64) ALDH1A1TSHRFBP1AKR1C3MAPT
Butadiene SCHEMBL9504523 0.94 ALDH1A1 (0.46) ALDH1A1TSHRFBP1AKR1C3MAPT
SCHEMBL180460 0.84 AKR1C3 (0.52) ALDH1A1TSHRFBP1AKR1C3MAPT
SCHEMBL8532034 0.83 ALDH1A1 (0.46) ALDH1A1TSHRFBP1AKR1C3MAPT
Propene SCHEMBL16585526 0.83 AKR1C3 (0.48) ALDH1A1TSHRFBP1AKR1C3MAPT
Styrene SCHEMBL8351921 0.82 ALDH1A1 (0.88) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL7086204 0.82 ALDH1A1 (0.88) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL15179 0.82 ALDH1A1 (0.88) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL7703256 0.82 ALDH1A1 (0.88) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL1615767 0.82 ALDH1A1 (0.88) ALDH1A1TSHRMAPTLMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0555386-A1 COMPOSITE MATERIALS INCLUDING FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS GREAT LAKES CHEMICAL CORPORATION (US) 1993-08-18 EP disclosed
EP-0535077-A1 FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS GREAT LAKES CHEMICAL CORPORATION (US) 1993-04-07 EP disclosed
WO-1992007915-A1 COMPOSITE MATERIALS INCLUDING FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS GREAT LAKES CHEMICAL CORPORATION (US) 1992-05-14 WO disclosed
US-5100986-A FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS GREAT LAKES CHEMICAL CORPORATION (US) 1992-03-31 US disclosed
WO-1991019748-A1 FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS GREAT LAKES CHEMICAL CORPORATION (US) 1991-12-26 WO disclosed
US-5066752-A FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS GREAT LAKES CHEMICAL CORPORATION (US) 1991-11-19 US disclosed