Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL9505984 | 0.94 | ALDH1A1 (0.58) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| SCHEMBL180460 | 0.90 | AKR1C3 (0.52) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| Styrene SCHEMBL9717243 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| Propene SCHEMBL16585526 | 0.88 | AKR1C3 (0.48) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| SCHEMBL8532034 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| Butadiene SCHEMBL10539483 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| SCHEMBL11354438 | 0.79 | MAOB (0.44) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| SCHEMBL29030357 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRFBP1AKR1C3MAPT | |
| SCHEMBL657316 | 0.76 | TP53 (0.57) | ALDH1A1FBP1AKR1C3MAPTHTT | |
| SCHEMBL3867763 | 0.75 | FBP1 (0.48) | ALDH1A1TSHRFBP1AKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555386-A1 | COMPOSITE MATERIALS INCLUDING FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS | GREAT LAKES CHEMICAL CORPORATION (US) | 1993-08-18 | — | — | EP | disclosed |
| EP-0535077-A1 | FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992007915-A1 | COMPOSITE MATERIALS INCLUDING FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS | GREAT LAKES CHEMICAL CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |
| US-5100986-A | FLAME RETARDANT BROMINATED STYRENE-BASED COATINGS | GREAT LAKES CHEMICAL CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991019748-A1 | FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5066752-A | FLAME RETARDANT BROMINATED STYRENE-BASED POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |