Styrene

Styrene

SCHEMBL9717243

BrC(Br)=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.64

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
TSHR P16473 2/20 0.64
FBP1 P09467 3/20 0.44
AKR1C3 P42330 1/20 0.43
MAPT P10636 3/20 0.41
HTT P42858 2/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
PAX8 Q06710 1/20 0.41
AKR1C1 Q04828 1/20 0.38
ESR1 P03372 1/20 0.38
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9505984 0.96 ALDH1A1 (0.58) ALDH1A1TSHRFBP1AKR1C3MAPT
Butadiene SCHEMBL9504523 0.88 ALDH1A1 (0.46) ALDH1A1TSHRFBP1AKR1C3MAPT
SCHEMBL180460 0.88 AKR1C3 (0.52) ALDH1A1TSHRFBP1AKR1C3MAPT
SCHEMBL8532034 0.87 ALDH1A1 (0.46) ALDH1A1TSHRFBP1AKR1C3MAPT
Propene SCHEMBL16585526 0.86 AKR1C3 (0.48) ALDH1A1TSHRFBP1AKR1C3MAPT
Styrene SCHEMBL4259704 0.83 ALDH1A1 (0.93) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL1456078 0.81 ALDH1A1 (0.70) ALDH1A1TSHRFBP1AKR1C3MAPT
Styrene SCHEMBL11144289 0.80 ALDH1A1 (1.00) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL10892600 0.80 ALDH1A1 (1.00) ALDH1A1TSHRMAPTLMNARECQL
Styrene SCHEMBL9776790 0.80 ALDH1A1 (1.00) ALDH1A1TSHRMAPTLMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291950-B1 PROCESS AND COMPOSITION FOR STABILIZATION OF AR-BROMINATED STYRENIC MONOMER AGAINST PREMATURE POLYMERIZATION GE CHEMICALS, INC. (US) 1992-08-12 EP disclosed
EP-0195815-B1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5069818-A CHEMICAL RESISTANCE, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1991-12-03 US disclosed
EP-0436136-A1 Compatibilized polyphenylene ehter resin/nylon resin blends containing aromatic phosphorous-containing compounds GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP disclosed
US-4824915-A COMPOUND CONTAINING ACYL HALIDE AND CARBOXYLIC ACID, ESTER, AMINE OR IMIDE GROUPS GENERAL ELECTRIC COMPANY (US) 1989-04-25 US disclosed
EP-0291950-A1 Process and composition for stabilization of ar-brominated styrenic monomer against premature polymerization GE CHEMICALS, INC. (US) 1988-11-23 EP disclosed
WO-1987007901-A1 FLAME RETARDANT POLYPHENYLENE ETHER-POLYSTYRENE BLENDS OF INCREASED HEAT RESISTANCE AND METHOD OF ACHIEVEMENT GENERAL ELECTRIC COMPANY (US) 1987-12-30 WO disclosed
EP-0224130-A2 Flame resistant blends of poly-carbonate resin and an alkenyl aromatic copolymer GENERAL ELECTRIC COMPANY (US) 1987-06-03 EP disclosed
US-4642358-A POLYAMIDES, POLYESTERS GENERAL ELECTRIC COMPANY (US) 1987-02-10 US disclosed
US-4600741-A ACYL MODIFIED POLYPHENYLENE ETHER AS COMPATIBILIZATION AGENT GENERAL ELECTRIC COMPANY (US) 1986-07-15 US disclosed
WO-1986002086-A1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1986-04-10 WO disclosed