Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 3/20 | 0.36 |
| ▸ | PGK2 | P07205 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034729 | 0.81 | MAOB (0.41) | GLAPGK1PGK2ALDH1A1L3MBTL1 | |
| SCHEMBL5403459 | 0.79 | ALDH1A1 (0.52) | TSHRALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9502876 | 0.79 | CCNT1 (0.42) | TSHR | |
| SCHEMBL2032607 | 0.76 | TSHR (0.50) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9503578 | 0.76 | CYP4F2 (0.37) | TSHRALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9503571 | 0.76 | CYP4F2 (0.37) | TSHRALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9502834 | 0.74 | NPSR1 (0.46) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9112737 | 0.71 | ALDH1A1 (0.47) | TSHRALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9165273 | 0.71 | GLA (0.39) | GLAPGK1PGK2MEN1KMT2A | |
| SCHEMBL225197 | 0.70 | TSHR (0.54) | TSHRALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |