Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503578 | 1.00 | CYP4F2 (0.37) | CYP4F2CYP4A11HDAC4MEF2DKCNA3 | |
| SCHEMBL9506003 | 0.76 | GLA (0.38) | TSHRALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL9506017 | 0.72 | PNP (0.53) | HDAC4PNP | |
| SCHEMBL9506021 | 0.72 | PNP (0.53) | HDAC4PNP | |
| SCHEMBL9259980 | 0.69 | ALDH1A1 (0.47) | CYP4F2CYP4A11HDAC4MEF2DTSHR | |
| SCHEMBL9259974 | 0.69 | ALDH1A1 (0.47) | CYP4F2CYP4A11HDAC4MEF2DTSHR | |
| SCHEMBL13859025 | 0.68 | TSHR (0.39) | CYP4F2CYP4A11HDAC4MEF2DTSHR | |
| SCHEMBL3782468 | 0.68 | HDAC4 (0.38) | CYP4F2CYP4A11HDAC4MEF2DTSHR | |
| SCHEMBL3782469 | 0.68 | HDAC4 (0.38) | CYP4F2CYP4A11HDAC4MEF2DTSHR | |
| SCHEMBL9502834 | 0.67 | NPSR1 (0.46) | HDAC4TSHRALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |