Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506051 | 1.00 | TNNC1 (0.45) | TNNC1CNR1CNR2KCNH2ABCG2 | |
| SCHEMBL9508213 | 0.89 | TNNC1 (0.44) | TNNC1CNR1CNR2KCNH2ABCG2 | |
| SCHEMBL9508218 | 0.89 | TNNC1 (0.44) | TNNC1CNR1CNR2KCNH2ABCG2 | |
| SCHEMBL9504802 | 0.88 | TNNC1 (0.44) | TNNC1ABCG2 | |
| SCHEMBL9508810 | 0.87 | TNNC1 (0.47) | TNNC1CNR1CNR2ABCG2 | |
| SCHEMBL9508814 | 0.87 | TNNC1 (0.47) | TNNC1CNR1CNR2ABCG2 | |
| SCHEMBL11020950 | 0.86 | PPARG (0.45) | KCNH2 | |
| SCHEMBL9504795 | 0.86 | PPARG (0.45) | KCNH2 | |
| SCHEMBL9508849 | 0.86 | PPARG (0.45) | KCNH2 | |
| SCHEMBL9508843 | 0.86 | PPARG (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |