SCHEMBL9508814

SCHEMBL9508814

CCCCCCCCC=Cc1ccc(C(=O)N(C)OC)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.47
MLYCD O95822 1/20 0.42
CNR1 P21554 3/20 0.40
CNR2 P34972 1/20 0.40
KDM4A O75164 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
ABCG2 Q9UNQ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508810 1.00 TNNC1 (0.47) TNNC1MLYCDCNR1CNR2KDM4A
SCHEMBL9506054 0.87 TNNC1 (0.45) TNNC1CNR1CNR2ABCG2
SCHEMBL9506051 0.87 TNNC1 (0.45) TNNC1CNR1CNR2ABCG2
SCHEMBL9508304 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9508944 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9508296 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9506969 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9506886 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9506072 0.86 TNNC1 (0.49) TNNC1
SCHEMBL9506896 0.86 TNNC1 (0.49) TNNC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161939-B1 ARYLHYDROXAMATES E.R. Squibb & Sons, Inc. (US) 1993-07-21 EP disclosed
CN-85104470-A The method for preparing arythydroxamtes 1986-10-01 CN disclosed
US-4607053-A L2POXYGENASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1986-08-19 US disclosed
EP-0161939-A2 Arylhydroxamates E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed