Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503158 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PTGER4SMN1; SMN2NPC1ALOX12 | |
| SCHEMBL9675548 | 0.81 | MAPT (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9361455 | 0.76 | ALDH1A1 (0.57) | ALDH1A1PTGER4SMN1; SMN2RAB9AHPGD | |
| SCHEMBL9502336 | 0.76 | GAA (0.44) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL9502131 | 0.76 | GAA (0.44) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL9502757 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL9503835 | 0.72 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2NPC1ALOX12RAB9A | |
| SCHEMBL9362336 | 0.71 | MAPT (0.45) | ALDH1A1SMN1; SMN2ALOX12HPGDMAPT | |
| SCHEMBL11571129 | 0.71 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL5164550 | 0.70 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |