Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506095 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBGAAMAPT | |
| SCHEMBL9361172 | 0.79 | GAA (0.69) | ALDH1A1SMN1; SMN2HTTLMNAPOLB | |
| SCHEMBL9361535 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HTTLMNAPOLB | |
| SCHEMBL2953971 | 0.74 | PDK1 (0.62) | ALDH1A1HTTLMNAPOLBPDK1 | |
| Bromide SCHEMBL12474018 | 0.73 | PDK1 (0.52) | ALDH1A1SMN1; SMN2HTTL3MBTL1LMNA | |
| SCHEMBL9503149 | 0.72 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HTTLMNAPOLB | |
| SCHEMBL9502336 | 0.71 | GAA (0.44) | ALDH1A1SMN1; SMN2HTTL3MBTL1GAA | |
| SCHEMBL14428567 | 0.71 | PDK1 (0.62) | ALDH1A1SMN1; SMN2HTTLMNAPDK1 | |
| SCHEMBL3603021 | 0.71 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTL3MBTL1LMNA | |
| SCHEMBL26247 | 0.71 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNAPOLBPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |