Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506095 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL9502277 | 0.78 | MAPT (0.35) | MAPTALDH1A1POLBNAMPTGAA | |
| SCHEMBL9503970 | 0.78 | MAPT (0.35) | MAPTALDH1A1POLBNAMPT | |
| SCHEMBL9365117 | 0.76 | MAPT (0.44) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL9502962 | 0.76 | CETP (0.42) | ALDH1A1GAAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL9692777 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1NAMPTKDM4EHTT | |
| SCHEMBL9692530 | 0.76 | CETP (0.42) | ALDH1A1GAAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL9502413 | 0.76 | CETP (0.42) | ALDH1A1GAAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL9505639 | 0.74 | HPGD (0.34) | MAPTPOLBNAMPTGAAHPGD | |
| SCHEMBL9503202 | 0.74 | KMT2A (0.36) | MAPTALDH1A1HPGDKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501822-A1 | Benzamide derivatives | RHONE POULENC RORER LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |