Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506512 | 0.89 | RAB9A (0.40) | FASNTRPV4CYP11B1CYP11B2EGLN2 | |
| SCHEMBL9506653 | 0.87 | RAB9A (0.45) | FASNKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9511660 | 0.87 | TRPV4 (0.39) | CYP2A6FASNTRPV4CYP11B1CYP11B2 | |
| SCHEMBL9506406 | 0.86 | MAPT (0.50) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10557295 | 0.85 | CYP11B1 (0.50) | CYP11B1CYP11B2XDH | |
| SCHEMBL9507836 | 0.85 | HSD17B10 (0.52) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9506361 | 0.85 | HSD17B10 (0.52) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9509921 | 0.85 | HSD17B10 (0.52) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9506648 | 0.85 | HSD17B10 (0.52) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9506395 | 0.85 | HSD17B10 (0.52) | KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | claimed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | claimed |
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | disclosed |