Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686398 | 0.87 | EGFR (0.50) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL8508241 | 0.81 | EGFR (0.47) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL5384052 | 0.80 | CYP3A4 (0.49) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL7717389 | 0.80 | ALDH1A1 (0.50) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL6675108 | 0.78 | EGFR (0.52) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL9417616 | 0.77 | CYP3A4 (0.50) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL472273 | 0.75 | MAPT (0.47) | KMT2AMEN1CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL11980711 | 0.74 | EGFR (0.63) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL10530057 | 0.74 | EGFR (0.41) | EGFRERBB2KMT2AMEN1CYP3A4 | |
| SCHEMBL5381358 | 0.73 | CYP3A4 (0.42) | EGFRERBB2KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206460-B1 | L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-08-11 | — | — | EP | disclosed |
| EP-0513872-A1 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4849345-A | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-07-18 | — | — | US | disclosed |