Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506412 | 0.87 | EGFR (0.48) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL8508241 | 0.84 | EGFR (0.47) | EGFRERBB2LMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5875622 | 0.83 | LMNA (0.46) | LMNAALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7717389 | 0.83 | ALDH1A1 (0.50) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL5384052 | 0.83 | CYP3A4 (0.49) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL6675108 | 0.81 | EGFR (0.52) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL9417616 | 0.80 | CYP3A4 (0.50) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL2682708 | 0.79 | ALDH1A1 (0.46) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL11484155 | 0.79 | HPGD (0.56) | EGFRERBB2LMNAALDH1A1MAPT | |
| SCHEMBL11980711 | 0.77 | EGFR (0.63) | EGFRERBB2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |