SCHEMBL472273

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1262575	0.85	ELANE (0.56)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL2170993	0.83	LMNA (0.59)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL11841636	0.79	MAPT (0.56)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL9645558	0.78	ALDH1A1 (0.49)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL27636153	0.78	HSD17B3 (0.50)	MAPTALDH1A1KDM4EMEN1KMT2A
	Hydrochloric Acid SCHEMBL11841634	0.78	MAPT (0.54)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL9645546	0.78	MAPT (0.53)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL4447324	0.77	LMNA (0.68)	ALDH1A1KMT2ARAB9ATSHRCYP1A2
	SCHEMBL24158	0.77	ELANE (0.48)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL6618980	0.77	CES2 (0.52)	MAPTALDH1A1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.