SCHEMBL9506440

SCHEMBL9506440

NC(S)=NS(=O)(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
LMNA P02545 3/20 0.53
MAPT P10636 2/20 0.53
KDM4E B2RXH2 1/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
ESR1 P03372 1/20 0.47
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
F2 P00734 11/20 0.47
PRSS1 P07477 11/20 0.47
PRSS2 P07478 11/20 0.47
PRSS3 P35030 11/20 0.47
AGO2 Q9UKV8 1/20 0.47
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11313668 1.00 ALDH1A1 (0.53) ALDH1A1LMNAMAPTKDM4EKMT2A
Water SCHEMBL11798808 0.98 ALDH1A1 (0.52) ALDH1A1LMNAMAPTKDM4EKMT2A
Water SCHEMBL11792457 0.98 ALDH1A1 (0.52) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL8932535 0.83 ALDH1A1 (0.57) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL10425537 0.83 F2 (0.67) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL30873930 0.78 ALDH1A1 (0.69) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL11029158 0.78 LMNA (0.52) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL11431146 0.76 PKM (0.41) ALDH1A1KDM4EKMT2ASMN1; SMN2F2
SCHEMBL11174973 0.75 LMNA (0.68) ALDH1A1LMNAMAPTKDM4EKMT2A
SCHEMBL7771730 0.74 ALDH1A1 (0.62) ALDH1A1LMNAMAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5001024-A None JP disclosed
JP-60006654-A None JP disclosed
JP-60067469-A None JP disclosed
JP-56164103-A None JP disclosed
JP-H051024-A SULFONAMIDE DERIVATIVE TOSOH CORP 1993-01-08 JP disclosed
US-4904299-A Herbicidal N-hydroxy-N'-sulfonylguanidines E. I. DU PONT DE NEMOURS AND CO. (US) 1990-02-27 US disclosed
EP-0117014-B1 HERBICIDAL N-HYDROXY-N'-SULFONYLGUANIDINES AND SULFONAMIDE INNER SALTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP disclosed
US-4750930-A Herbicidal N-hydroxy-N'-sulfonylguanidines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-14 US disclosed
US-4689070-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-25 US disclosed
US-4568381-A APPLIED TO RICE TO KILL WEEDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-02-04 US disclosed
US-4559079-A Substituted phenylsulfonyl guanidine herbicides and intermeditates therefor NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-12-17 US disclosed
JP-S6067469-A PRODUCTION OF SUBSTITUTED PHENYLSULFONYLUREA DERIVATIVE NIPPON TOKUSHU NOYAKU SEIZO KK 1985-04-17 JP disclosed
JP-S606654-A SUBSTITUTED PHENYLSULFONYLGUANIDINE DERIVATIVE, ITS INTERMEDIATE, THEIR PREPARATION AND HERBICIDE NIPPON TOKUSHU NOYAKU SEIZO KK 1985-01-14 JP disclosed
EP-0117014-A1 Herbicidal N-hydroxy-N'-sulfonylguanidines and sulfonamide inner salts E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-29 EP disclosed
JP-S56164103-A FUNGICIDE FOR PLANT BLIGHT MEIJI SEIKA KAISHA LTD 1981-12-17 JP disclosed