SCHEMBL950657

SCHEMBL950657

CCCCn1ccnc1C(C)SC

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
POLB P06746 1/20 0.57
KMT2A Q03164 1/20 0.57
TLR8 Q9NR97 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.36
CYP1A2 P05177 1/20 0.36
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424656 0.83 ALDH1A1 (0.59) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL27721562 0.80 KMT2A (0.56) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL27353957 0.79 ALDH1A1 (0.51) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL25067265 0.78 TLR8 (0.59) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL3307602 0.77 ALDH1A1 (0.53) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL28078170 0.77 TLR8 (0.57) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL18250324 0.77 TLR8 (0.57) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL5824074 0.77 TLR8 (0.57) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL27679742 0.75 KMT2A (0.54) ALDH1A1POLBKMT2ATLR8SMN1; SMN2
SCHEMBL1466191 0.75 ALDH1A1 (0.54) ALDH1A1POLBKMT2ATLR8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110021483-A1 Platinum (IV) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-01-27 US disclosed
CN-101778857-A Platinum (IV) complex compound PLATCO TECHNOLOGIES PROPRIETAR 2010-07-14 CN disclosed
EP-2170913-A1 PLATINUM (IV) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2010-04-07 EP disclosed
WO-2008155727-A1 PLATINUM (IV) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021483-A1 Platinum (IV) Complexes OTC, OAT, SLC25A11 ALDH1A1 3109/4885POLB 225/4885KMT2A 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.