SCHEMBL9506862

SCHEMBL9506862

NC(=O)c1cc(O)nc(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.45
PARP1 P09874 6/20 0.43
CYP3A4 P08684 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PTPN11 Q06124 2/20 0.40
TSHR P16473 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
KDM4B O94953 1/20 0.38
KDM5C P41229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27461884 0.84 LCK (0.38) LCKPARP1CYP3A4SMN1; SMN2PTPN11
SCHEMBL813450 0.76 PARP1 (0.53) LCKPARP1CYP3A4SMN1; SMN2TSHR
Citrazinic Acid SCHEMBL185046 0.76 TSHR (0.56) LCKSMN1; SMN2TSHRPOLBMAPT
Citrazinic Acid SCHEMBL11217659 0.74 TSHR (0.54) SMN1; SMN2TSHRPOLBMAPTHSD17B10
SCHEMBL13446636 0.74 CA5A (0.56) CYP3A4SMN1; SMN2MAPTL3MBTL1LMNA
SCHEMBL2088488 0.74 SMN1; SMN2 (0.46) LCKPARP1CYP3A4SMN1; SMN2TSHR
Citrazinic Acid SCHEMBL10818912 0.74 TSHR (0.54) SMN1; SMN2TSHRPOLBMAPTHSD17B10
SCHEMBL7378255 0.73 MKNK1 (0.51) LCKMKNK1MKNK2
SCHEMBL1807480 0.72 PARP1 (0.58) LCKPARP1CYP3A4SMN1; SMN2TSHR
SCHEMBL441865 0.72 PARP1 (0.58) LCKPARP1CYP3A4SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4221860-A COLOR REVERSAL, DEVELOPMENT WITH COMPETING COUPLER, EMULSION CONTAINING BLUE-SENSITIVE METHYLENE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US claimed
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed
EP-0019299-B1 PHOTOGRAPHIC SILVER HALIDE MATERIAL HAVING A COLOR FILTER LAYER OR AN ANTIHALATION DYE LAYER CIBA-GEIGY AG (CH) 1983-07-27 EP disclosed
EP-0019298-B1 PHOTOGRAPHIC SILVER HALIDE MATERIAL HAVING A FILTER LAYER OR AN ANTIHALATION LAYER CIBA-GEIGY AG (CH) 1983-03-16 EP disclosed
EP-0013936-B1 REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS BAYER AG (DE) 1982-09-22 EP disclosed
US-4327018-A Azo dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-04-27 US disclosed
US-4299764-A Azo reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US disclosed
US-4294916-A METHINE DYES CIBA-GEIGY AG (CH) 1981-10-13 US disclosed
US-4294917-A METHINE DYES CIBA-GEIGY AG (CH) 1981-10-13 US disclosed
EP-0019299-A1 Photographic silver halide material having a color filter layer or an antihalation dye layer CIBA-GEIGY AG (CH) 1980-11-26 EP disclosed
EP-0019298-A1 Photographic silver halide material having a filter layer or an antihalation layer CIBA-GEIGY AG (CH) 1980-11-26 EP disclosed
US-4233399-A Photographic elements containing amino-substituted hydroxy-pyridones CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-11 US disclosed
US-4221860-A COLOR REVERSAL, DEVELOPMENT WITH COMPETING COUPLER, EMULSION CONTAINING BLUE-SENSITIVE METHYLENE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US disclosed
EP-0013936-A1 Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed
US-4160643-A FOR POLYMERS OF ACRYLONITRILE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-10 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed