SCHEMBL950710

SCHEMBL950710

CNc1c(Br)cc(Br)cc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.55
AKR1C2 P52895 3/20 0.55
AKR1C1 Q04828 3/20 0.55
AKR1C4 P17516 2/20 0.55
HSD17B10 Q99714 2/20 0.53
GPR35 Q9HC97 2/20 0.40
KDM4E B2RXH2 2/20 0.40
GLA P06280 1/20 0.40
HSPD1 P10809 1/20 0.39
HSPE1 P61604 1/20 0.39
LCK P06239 2/20 0.39
FYN P06241 1/20 0.39
PTPN1 P18031 1/20 0.38
MYC P01106 1/20 0.38
NR4A1 P22736 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9276237 0.83 AKR1C3 (0.48) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL12912146 0.83 MYC (0.50) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL762107 0.83 AKR1C3 (0.44) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL8528629 0.81 AKR1C3 (0.52) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL7985780 0.78 AKR1C3 (0.52) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL10799251 0.75 AKR1C2 (0.49) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL9279442 0.74 PTPN1 (0.43) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL2226763 0.74 AKR1C3 (0.61) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL30780100 0.74 TTR (0.56) HSD17B10GPR35KDM4EMEN1KMT2A
SCHEMBL17824683 0.73 PRNP (0.46) AKR1C3HSD17B10KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
US-4089078-A Arylazopyrazolone dyes for polyester AMERICAN COLOR & CHEMICAL CORPORATION (US) 1978-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 AKR1C3 828/4885AKR1C2 643/4885AKR1C1 541/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT AKR1C3 2377/4885AKR1C2 1520/4885AKR1C1 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.