Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241687 | 0.86 | IDO1 (0.59) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL9680973 | 0.86 | IDO1 (0.59) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL17842434 | 0.84 | IDO1 (0.45) | IDO1TDO2ALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL4010346 | 0.84 | CA12 (0.48) | MEN1KMT2AALDH1A1CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL32664910 | 0.84 | IDO1 (0.49) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL28264344 | 0.82 | KMT2A (0.49) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL414370 | 0.81 | MEN1 (0.48) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL2153572 | 0.80 | ACP3 (0.56) | ALDH1A1CYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL19282953 | 0.80 | ACP3 (0.56) | ALDH1A1CYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL3227491 | 0.80 | CYP2D6 (0.50) | MEN1KMT2AALDH1A1CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331073-B1 | BENZHYDRYLAMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5051526-A | Reagents for solid phase synthesis of polypeptides | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4965405-A | INTERMEDIATE FOR POLYPEPTIDE SYNTHESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0331073-A2 | Benzhydrylamine derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |