Sugi Predict

Sugi Predict / Compounds / SCHEMBL9680973

SCHEMBL9680973

SCHEMBL9680973

COc1ccccc1C(N)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.59
▸ TDO2 P48775 1/20 0.59
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA12 O43570 1/20 0.48
▸ CA4 P22748 1/20 0.48
▸ CA7 P43166 1/20 0.48
▸ CA9 Q16790 1/20 0.48
▸ CA14 Q9ULX7 1/20 0.48
▸ CYP19A1 P11511 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ ADRA2B P18089 1/20 0.45
▸ PTGS1 P23219 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ ACHE P22303 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20241687 1.00 IDO1 (0.59) IDO1TDO2CA1CA2CA12
SCHEMBL7029643 0.87 IDO1 (0.51) IDO1TDO2CA1CA2CA12
SCHEMBL9507120 0.86 MEN1 (0.48) IDO1TDO2CA1CA2CA12
SCHEMBL17842434 0.85 IDO1 (0.45) IDO1TDO2CA1CA2CA12
Hydrochloric Acid SCHEMBL32664910 0.85 IDO1 (0.49) IDO1TDO2CA1CA2CA12
SCHEMBL19665104 0.82 ACHE (0.46) IDO1TDO2ALDH1A1TDP1L3MBTL1
SCHEMBL414370 0.82 MEN1 (0.48) IDO1TDO2CA1CA2CA12
Hydrochloric Acid SCHEMBL17871836 0.81 IDO1 (0.45) IDO1TDO2ALDH1A1TDP1L3MBTL1
SCHEMBL9719141 0.79 DPP4 (0.55) DPP4
SCHEMBL3039320 0.78 IDO1 (0.58) IDO1TDO2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 — — US claimed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 — — EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 — — EP claimed
US-20240417383-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2024-12-19 — — US disclosed
EP-3770146-B1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF ASTELLAS ENG SMALL MOLECULES US INCORPORATED (US) 2024-07-24 — — EP disclosed
US-11912681-B2 Crystalline and salt forms of PPAR agonist compounds MITOBRIDGE, INC. (US) 2024-02-27 — — US disclosed
US-20230373948-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Astellas Engineered Small Molecules US, Incorporated 2023-11-23 — — US disclosed
US-20230257360-A1 CRYSTALLINE AND SALT FORMS OF PPAR AGONIST COMPOUNDS Astellas Engineered Small Molecules US, Incorporated 2023-08-17 — — US disclosed
EP-3795566-B1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF MITOBRIDGE INC (US) 2023-04-19 — — EP disclosed
US-11578052-B2 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof MITOBRIDGE, INC. (US) 2023-02-14 — — US disclosed
CN-109843857-B Crystalline and salt forms of PPAR agonist compounds 米托布里奇公司 2023-01-06 — — CN disclosed
WO-2013019682-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. (US) 2013-02-07 — — WO disclosed
WO-2013019682-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. (US) 2013-02-07 — — WO disclosed
US-5153226-A Administering as anticholesterol agents, for atherosclerosis WARNER-LAMBERT COMPANY (US) 1992-10-06 — — US disclosed
EP-0431605-A2 1-Azabicyclo[m.n.O]alkane derivatives, their salts and process for preparing them SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1991-06-12 — — EP disclosed
EP-0415413-A1 Acat inhibitors WARNER-LAMBERT COMPANY (US) 1991-03-06 — — EP disclosed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 — — US disclosed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 — — US disclosed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 — — EP disclosed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912681-B2 Crystalline and salt forms of PPAR agonist compounds PPARD, PPARA, PPARG IDO1 4780/4885TDO2 4864/4885CA1 4245/4885
US-20240417383-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF PPARG, PPARD, PPARA IDO1 4598/4885TDO2 4582/4885CA1 4884/4885
US-20230373948-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF PPARG, PPARD, PPARA IDO1 4598/4885TDO2 4582/4885CA1 4884/4885
US-11578052-B2 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof PPARG, PPARD, PPARA IDO1 4598/4885TDO2 4582/4885CA1 4884/4885
US-20230257360-A1 CRYSTALLINE AND SALT FORMS OF PPAR AGONIST COMPOUNDS PPARD, PPARA, PPARG IDO1 4780/4885TDO2 4864/4885CA1 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.