Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727511 | 0.91 | CYP2C9 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10718455 | 0.80 | THRA (0.45) | THRATHRB | |
| SCHEMBL9507157 | 0.79 | DRD2 (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9507163 | 0.79 | DRD2 (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10788192 | 0.79 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8734277 | 0.79 | CYP3A4 (0.33) | GAAALDH1A1MAPT | |
| SCHEMBL8734276 | 0.79 | CYP3A4 (0.33) | GAAALDH1A1MAPT | |
| SCHEMBL10867047 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2CES2CES1ALDH1A1MAPT | |
| SCHEMBL10789569 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2CES2CES1ALDH1A1MAPT | |
| SCHEMBL10345113 | 0.78 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4917819-A | Cyclohexane derivative and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0205998-B1 | CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4797228-A | Cyclohexane derivative and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0205998-A1 | Cyclohexane derivative and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-12-30 | — | — | EP | disclosed |