SCHEMBL9507246

SCHEMBL9507246

CN=Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
ALDH1A1 P00352 1/20 0.49
PTGS1 P23219 4/20 0.45
PTGS2 P35354 3/20 0.45
CYP1A2 P05177 1/20 0.44
AHR P35869 1/20 0.42
NQO2 P16083 2/20 0.42
FBP1 P09467 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507242 1.00 LMNA (0.49) LMNAALDH1A1PTGS1PTGS2CYP1A2
SCHEMBL22389454 0.80 SMN1; SMN2 (0.48) LMNAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL8782103 0.79 GRIN2D (0.55) LMNAALDH1A1CYP1A2MEN1KMT2A
SCHEMBL8782107 0.79 GRIN2D (0.55) LMNAALDH1A1CYP1A2MEN1KMT2A
SCHEMBL27662796 0.79 LMNA (0.50) LMNAALDH1A1PTGS1PTGS2CYP1A2
SCHEMBL25094429 0.79 GRIN2D (0.55) LMNAALDH1A1CYP1A2MEN1KMT2A
SCHEMBL4834072 0.77 PTGS2 (0.49) LMNAALDH1A1PTGS1PTGS2CYP1A2
SCHEMBL2117755 0.77 LMNA (0.53) LMNAALDH1A1PTGS1PTGS2CYP1A2
SCHEMBL3975476 0.77 LMNA (0.53) LMNAALDH1A1PTGS1PTGS2CYP1A2
SCHEMBL17712792 0.77 LMNA (0.53) LMNAALDH1A1PTGS1PTGS2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066303-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF NIHON NOHYAKU CO., LTD. (JP) 2025-02-27 US disclosed
EP-4458809-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2024-11-06 EP disclosed
CN-118696031-A Aryltetrahydropyridine derivative or salt thereof, pest control agent containing the same, and method for using the same 日本农药株式会社 2024-09-24 CN disclosed
WO-2023127806-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 日本農薬株式会社 2023-07-06 WO disclosed
EP-0314422-B1 N-PHENYLALKYLBENZAMIDE FUNGICIDES DOWELANCO (US) 1993-07-28 EP disclosed
US-4957533-A THIOAMIDES, AMIDINES ELI LILLY AND COMPANY (US) 1990-09-18 US disclosed
EP-0314422-A2 N-phenylalkylbenzamide fungicides DOWELANCO (US) 1989-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066303-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF TYR, TH, PRXL2A LMNA 4378/4885ALDH1A1 1569/4885PTGS1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.