SCHEMBL9507295

SCHEMBL9507295

Cc1cc(O)c(C)c2c1CCC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.40
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 3/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
G6PD P11413 1/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP2C19 P33261 1/20 0.37
CCR6 P51684 1/20 0.37
HIF1A Q16665 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HTT P42858 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12909512 0.76 ALDH1A1 (0.37) ACHEALDH1A1MAPTKDM4ECYP3A4
SCHEMBL18920124 0.76 PNMT (0.39) ACHEKDM4EHSD17B10CYP1A2CYP2D6
Bromide SCHEMBL18920128 0.74 PNMT (0.38) ACHEKDM4EHSD17B10CYP1A2CYP2D6
SCHEMBL21730241 0.73 CA1 (0.42) ACHEALDH1A1MAPTKDM4ECYP1A2
SCHEMBL8742876 0.73 MEN1 (0.40) ACHEALDH1A1MAPTKDM4ECYP3A4
SCHEMBL30288142 0.71 ALOX5 (0.35) ACHEALDH1A1MAPTKDM4ECYP3A4
SCHEMBL14283938 0.71 ALDH1A1 (0.46) ACHEALDH1A1MAPTKDM4EHPGD
SCHEMBL8116294 0.71 ALOX5 (0.38) ACHEALDH1A1MAPTKDM4ECYP3A4
SCHEMBL30995620 0.70 CA12 (0.49) ACHEMAPTKDM4ECYP3A4HPGD
SCHEMBL27353018 0.70 CA12 (0.49) ACHEMAPTKDM4ECYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295037-B1 PHENOL DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1993-08-18 EP disclosed