SCHEMBL9507356

SCHEMBL9507356

Nc1ccc(Oc2ccccc2-c2ccccc2)c(N)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
PTGDR2 Q9Y5Y4 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
BRD4 O60885 1/20 0.40
SCN9A Q15858 1/20 0.39
MAOA P21397 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27966488 0.87 NCOA1 (0.47) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL21831937 0.86 NCOA1 (0.53) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL28084830 0.85 NCOA1 (0.56) NCOA1NCOA3ALDH1A1HSD17B10TP53
SCHEMBL25135311 0.84 NCOA1 (0.54) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL5072276 0.83 NCOA1 (0.61) NCOA1NCOA3ALDH1A1HSD17B10TP53
SCHEMBL4324881 0.83 PTGDR2 (0.60) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL13261645 0.83 NCOA1 (0.50) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL9298320 0.83 NCOA1 (0.58) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10
SCHEMBL5707641 0.83 ALDH1A1 (0.46) NCOA1NCOA3ALDH1A1HSD17B10TP53
SCHEMBL29363353 0.81 NCOA1 (0.52) NCOA1NCOA3PTGDR2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843912-A Polyurethane material with woven cross-linked structure and preparation method thereof 中国科学院兰州化学物理研究所 2024-04-09 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-114395215-A Sulfone ether epoxy adhesive and UHMWPE fiber reinforced bulletproof composite material and preparation method thereof 兰溪聪普新材料有限公司 2022-04-26 CN claimed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN claimed
CN-103254573-B A kind of High-temperature-resmicant micant plate matrix resin and preparation method thereof 东华大学 2016-08-10 CN claimed
CN-104228216-B A kind of low-loss high-performance copper coated foil plate and preparation method thereof 东华大学 2016-06-08 CN claimed
CN-104559059-A High-temperature-resistant matrix resin for high-Tg copper-clad plate and preparation method of high-temperature-resistant matrix resin NAT UNIV DONG HWA 2015-04-29 CN claimed
CN-103146331-A 4,4'-bis(2,4-diamidophenoxy)biphenyl high-temperature-resistant epoxy adhesive and preparation method thereof UNIV DONGHUA 2013-06-12 CN claimed
EP-0200204-B1 MELT-FUSIBLE COPOLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-01 EP claimed
EP-0122060-B1 MELT-FUSIBLE POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-07 EP claimed
EP-0200204-A2 Melt-fusible copolyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-05 EP claimed
US-4576857-A ETHER AMINES AND PYROMELLITIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-18 US claimed
EP-0122060-A2 Melt-fusible polyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-17 EP claimed
CN-117843912-A Polyurethane material with woven cross-linked structure and preparation method thereof 中国科学院兰州化学物理研究所 2024-04-09 CN disclosed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
CN-114395215-A Sulfone ether epoxy adhesive and UHMWPE fiber reinforced bulletproof composite material and preparation method thereof 兰溪聪普新材料有限公司 2022-04-26 CN disclosed
EP-0200204-A2 Melt-fusible copolyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-05 EP disclosed
US-4576857-A ETHER AMINES AND PYROMELLITIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-18 US disclosed
US-4485140-A BINDERS FOR COMPOSITES IN AEROSPACE AND AUTOMOBILE INDUSTRIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-27 US disclosed
EP-0122060-A2 Melt-fusible polyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-17 EP disclosed