Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9291049 | 0.98 | KDM4E (0.42) | KDM4ELMNASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL9505830 | 0.93 | LMNA (0.47) | KDM4ELMNASMN1; SMN2TP53USP2 | |
| Bromide SCHEMBL9290773 | 0.91 | LMNA (0.46) | KDM4ELMNASMN1; SMN2TP53USP2 | |
| SCHEMBL9290896 | 0.89 | HDAC2 (0.43) | KDM4ESMN1; SMN2HSD17B10PAOXHPGD | |
| SCHEMBL2905467 | 0.86 | KDM4E (0.45) | KDM4ELMNASMN1; SMN2HSD17B10HPGD | |
| SCHEMBL2905190 | 0.84 | ALDH1A1 (0.44) | KDM4ELMNASMN1; SMN2HSD17B10RAD52 | |
| Iodide SCHEMBL4008476 | 0.84 | KDM4E (0.44) | KDM4ELMNASMN1; SMN2HSD17B10HPGD | |
| Iodide SCHEMBL4010788 | 0.83 | ALDH1A1 (0.43) | KDM4ELMNASMN1; SMN2HSD17B10RAD52 | |
| SCHEMBL1176628 | 0.82 | SMN1; SMN2 (0.45) | KDM4ELMNASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL9861586 | 0.81 | LMNA (0.65) | KDM4ELMNASMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | claimed |