Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9290773 | 0.98 | LMNA (0.46) | LMNAKDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL9507395 | 0.93 | KDM4E (0.43) | LMNAKDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL2905467 | 0.92 | KDM4E (0.45) | LMNAKDM4ESMN1; SMN2HPGDDUSP3 | |
| Bromide SCHEMBL9291049 | 0.91 | KDM4E (0.42) | LMNAKDM4ESMN1; SMN2TP53HPGD | |
| Iodide SCHEMBL4008476 | 0.91 | KDM4E (0.44) | LMNAKDM4ESMN1; SMN2HPGDDUSP3 | |
| SCHEMBL2905190 | 0.91 | ALDH1A1 (0.44) | LMNAKDM4ESMN1; SMN2ALDH1A1MAPT | |
| Iodide SCHEMBL4010788 | 0.89 | ALDH1A1 (0.43) | LMNAKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9861586 | 0.88 | LMNA (0.65) | LMNAKDM4ESMN1; SMN2HPGDDUSP3 | |
| Bromide SCHEMBL9290882 | 0.86 | LMNA (0.63) | LMNAKDM4ESMN1; SMN2HPGDDUSP3 | |
| Bromide SCHEMBL9723331 | 0.85 | LMNA (0.61) | LMNAKDM4ESMN1; SMN2HPGDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | claimed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | claimed |