Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369406 | 0.98 | LMNA (0.49) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1720153 | 0.86 | AKT1 (0.52) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6678865 | 0.82 | AKT1 (0.48) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| Propene SCHEMBL11475202 | 0.78 | LMNA (0.44) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6387849 | 0.76 | GAA (0.45) | LMNATDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL27624213 | 0.76 | MEN1 (0.51) | LMNATDP1ALDH1A1PGRADRA2A | |
| SCHEMBL9502272 | 0.75 | TDP1 (0.47) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9093296 | 0.75 | LMNA (0.51) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11287380 | 0.74 | LMNA (0.54) | LMNAAKT1TDP1L3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28060786 | 0.74 | TDP1 (0.50) | LMNAAKT1TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549808-A1 | TRANSPARENT PLASTIC MATERIAL | SEIKO EPSON CORPORATION (JP) | 1993-07-07 | — | — | EP | disclosed |