Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089105 | 0.82 | ALDH1A1 (0.47) | LMNAADRA2BSMN1; SMN2NPSR1MAPT | |
| SCHEMBL5224169 | 0.81 | PGR (0.48) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL27940323 | 0.80 | CES2 (0.45) | MAPTCES2CES1ALDH1A1TSHR | |
| SCHEMBL26676884 | 0.80 | LMNA (0.49) | LMNAAKT1PGRADRA2AADRA2B | |
| SCHEMBL11287380 | 0.78 | LMNA (0.54) | LMNAAKT1PGRADRA2AADRA2B | |
| SCHEMBL1720153 | 0.78 | AKT1 (0.52) | LMNAAKT1PGRADRA2AADRA2B | |
| SCHEMBL13174973 | 0.78 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTTDP1ALDH1A1 | |
| SCHEMBL96304 | 0.78 | TDP1 (0.54) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL6880869 | 0.78 | PGR (0.46) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL14703165 | 0.78 | PGR (0.46) | LMNAPGRADRA2AADRA2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709087-B1 | OLEFIN POLYMERIZATION CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2008-09-03 | — | — | EP | disclosed |
| US-5490952-A | REDUCING COMPLEX OF COPPER HALIDE OR CYANIDE AND ALKALI HALIDE WITH ALKALI SALT OF AROMATIC ANION; FOR SYNTHESIZING HIGHLY FUNCTIONAL ORGANIC COMPOUNDS | UNIVERSITY OF NEBRASKA (US) | 1996-02-13 | — | — | US | disclosed |
| WO-1992019623-A1 | HIGHLY REACTIVE FORM OF COPPER AND REAGENTS THEREOF | REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1992-11-12 | — | — | WO | disclosed |