Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507552 | 0.81 | KMT2A (0.45) | HTTMEN1KMT2ACA1CA2 | |
| SCHEMBL28373028 | 0.77 | HTT (0.59) | HTTMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL28498471 | 0.73 | HTT (0.57) | HTTIDO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6748170 | 0.70 | LOXL2 (0.47) | HTTIDO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL515031 | 0.69 | LOXL2 (0.53) | HTTIDO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6940919 | 0.69 | LOXL2 (0.53) | HTTIDO1MEN1KMT2ALOXL2 | |
| SCHEMBL28357735 | 0.69 | LOXL2 (0.57) | HTTIDO1MEN1KMT2ALOXL2 | |
| SCHEMBL5872160 | 0.68 | HTT (0.51) | HTTIDO1KMT2AL3MBTL1LOXL2 | |
| SCHEMBL2995728 | 0.68 | MAPT (0.48) | HTTMEN1KMT2ALOXL2MAPT | |
| SCHEMBL9303069 | 0.68 | POLB (0.48) | HTTKMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337820-B1 | PENTAFLUOROPHENYL DERIVATIVES, METHODS OF PRODUCTION OF SUCH DERIVATIVES INCLUDING OPTICALLY ACTIVE DERIVATIVES, AND METHOD OF OPTICAL RESOLUTION OF CHIRAL CARBOXYLIC ACIDS | NIKKO KYODO CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5041641-A | Pentafluorophenyl derivatives, methods of production thereof, and method of optical resolution of chiral carboxylic acids | NIPPON MINING COMPANY LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0337820-A1 | Pentafluorophenyl derivatives, methods of production of such derivatives including optically active derivatives, and method of optical resolution of chiral carboxylic acids | NIKKO KYODO CO., LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |