SCHEMBL9507556

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(NC(=N)N)C(=O)C(C)ON)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NTSR2	O95665	19/20	0.58

▸	NTSR1	P30989	19/20	0.58

▸	SORT1	Q99523	17/20	0.58

▸	AGTR1	P30556	1/20	0.53

▸	AGTR2	P50052	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8741230	0.85	C5AR1 (0.59)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL31544391	0.85	AGTR1 (0.62)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL29359023	0.85	AGTR2 (0.66)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL29649735	0.85	AGTR1 (0.62)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL9010599	0.85	AGTR1 (0.62)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL9010604	0.85	AGTR1 (0.62)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL9010597	0.84	LNPEP (0.64)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL9010601	0.84	LNPEP (0.64)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL29569062	0.84	C5AR1 (0.65)	NTSR2NTSR1SORT1AGTR1AGTR2
SCHEMBL29976356	0.84	C5AR1 (0.57)	NTSR2NTSR1SORT1AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0561896-A1	USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION	SMITHKLINE BEECHAM PLC (GB)	1993-09-29	—	—	EP	disclosed