Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 7/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505457 | 0.87 | CASP1 (0.56) | CASP1GLAKMT2A | |
| SCHEMBL4590122 | 0.86 | KMT2A (0.59) | GLAKMT2AFAAHPOLB | |
| SCHEMBL31437081 | 0.82 | FFAR1 (0.52) | CASP1KMT2A | |
| SCHEMBL6996476 | 0.80 | KMT2A (0.47) | CASP1GLAKMT2AFAAH | |
| SCHEMBL4589632 | 0.80 | KMT2A (0.54) | CASP1GLAKMT2AFAAH | |
| SCHEMBL9508841 | 0.79 | CASP1 (0.52) | CASP1KMT2APOLB | |
| SCHEMBL132095 | 0.78 | POLB (0.51) | GLAKMT2APTPN1POLB | |
| SCHEMBL11077052 | 0.78 | ACACB (0.52) | GLAKMT2AFAAHPOLB | |
| SCHEMBL13220483 | 0.76 | TBXA2R (0.57) | TBXA2RTBXAS1KMT2APTPN1POLB | |
| SCHEMBL12201807 | 0.76 | ESRRG (0.53) | CASP1GLAKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278911-B1 | BICYCLIC BETA-LACTAM CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-4965260-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0278911-A1 | Bicyclic beta-lactam carboxylic acids | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |